Selected publications of Zylacta team


'Biodegradable glucosaminemuramyl peptides for apoptosis modulation. Slesarev et al., US Patent 7,112,564 (US Patent 7,112,564).

'БИОДЕГРАДИРУЕМЫЕ ГЛЮКОЗАМИНМУРАМИЛПЕПТИДЫ ДЛЯ МОДУЛЯЦИИ АПОПТОЗА', Slesarev et al., Russian patent 2363490 (13) C2 (Russian patent 2363490).

Research on probiotics

'Complete Genome Sequence of Lactobacillus acidophilus FSI4, Isolated from Yogurt.', Iartchouk et al., Genome Announc. 2015 Nov 19;3(6), (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653774/).

'Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growth.', Lee et al., BMC Genomics. 2008 May 27;9:247, (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430713/).

'Comparative genomics of the lactic acid bacteria', Makarova et al., Proc. Natl. Acad. Sci. USA, 2006, 103 (42), 15611-15616, (http://www.pnas.org/content/103/42/15611.full).

'Inhibition of systemic TNF-alpha cytotoxicity in cancer patients by D-peptidoglycan', Slesarev et al., Med Oncol. 1998 Apr;15(1):37-43, (http://link.springer.com/article/10.1007/BF02787343).

Hybrid enzymes (elements of eDD™ technology)

'Cooperation between catalytic and DNA binding domains enhances thermostability and supports DNA synthesis at higher temperatures by thermostable DNA polymerases', Pavlov et al., Biochemistry, 2012, 51 (10), 2032-2043, 2015, 22, 1-8, (http://pubs.acs.org/doi/abs/10.1021/bi2014807).

'Helix–hairpin–helix motifs confer salt resistance and processivity on chimeric DNA polymerases', Pavlov et al., Proc. Natl. Acad. Sci. USA, 2002, 99 (21), 13510-13515, (http://www.pnas.org/content/99/21/13510.full).

'Stabilization of Taq DNA polymerase at high temperature by protein folding pathways from a hyperthermophilic archaeon, Pyrococcus furiosus', Laksanalamai et al., Biotechnology and bioengineering, 2006, 93 (1), 1-5 (http://www.umventures.org/sites/umventures.com/files/attachments/document%2811%29.pdf).

Other related publications

'Genome sequence of a hyperthermophilic archaeon, Thermococcus nautili 30-1, that produces viral vesicles', Oberto et al., Genome announcements, 2014, 2 (2), e00243-14 (http://genomea.asm.org/content/2/2/e00243-14.full).

'High-throughput production of optimized primers (fimers) for whole-genome direct sequencing', Polushin et al., (http://link.springer.com/protocol/10.1385/1-59259-823-4:291).

'Automated sequencing directly from genomic DNA and through difficult regions', Kozyavkin et al., FASEB JOURNAL, 1998 12 (8), A1367-A1367.